Micronized Beta Glucan and Other Misnomers

Micronized beta glucan is completely made-up terminology used by certain companies for marketing purposes only. There is absolutely no research showing any benefit to “micronized” beta glucan whatsoever. Size, which is what “micronized” is referring to, has zero impact on the efficacy of a beta glucan product. These companies are knowingly misleading their consumers to try and gain an advantage. It’s extremely sad that companies go this far to deceive innocent people. Our Beta Glucan has been scientifically proven to work every single time based on real research and studies. Any marketing we use is based directly from the peer-reviewed studies that have been conducted by disinterested third-party researchers. We always strive to do things with complete transparency and integrity.

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As Answered By
Dr. Vaclav Vetvicka

I believe the most misleading thing on the internet to be, the misuse of the term “Micronized.” This marketing gimmick has been out there for as long as I’ve been involved in the Beta Glucan business. I don’t even believe “micronized” to be a word. For those who are unfamiliar, a micron is a measurement of length. It’s like a foot, an inch, or a yard; if I told you something was inch-ized or yard-ized, what in the world would that be telling you? It would mean NOTHING. Hence, to be using such a term in order to describe a compound you sell, doesn’t really mean anything. Is it one micron, two microns, or 200 microns? Now if the term Sub-Micronized was used, it would indicate the diameter of a particle less than one micron. I’ve Got News For all of You

All Baker’s Yeast cells are the same size: 2-4 Microns. Therefore, all Beta Glucans, unless they have been crushed up by process, are going to be 2 to 4 Microns. Now I see some websites talking about, “Oh! You know they’re throwing boulders [Big Microns] and we’re shooting bullets [“Micronized” Microns].” It is all “Stupid Hogwash,” preying on the ignorance of the public. The bottom line is, your immune cells, we’re talking about the phagocytes; can actually consume two, three, four, and maybe even more of these 2-4 micron-sized particles. How do I know that? Again, it is published in peer-reviewed literature.

Another example is a study published out of Japan where scientists made their own beta glucan, without discussing their source or how it was purified. They fed a particular prescription NSAID (Non-Steroidal Anti-Inflammatory Drug) to some rats while at the same time, they gave them their self-made Beta Glucan: All of The Rats Died! Due to this flawed study, many remarks were made claiming beta glucan should not be taken with Tylenol, Aspirin, or Ibuprofen. So, I asked that the experiment be repeated with Beta-1, 3D Glucan and in fact, the study was published and None of The Rats Died! That misinformation about not being able to take beta glucan with common NSAIDs is as bogus as the day is long.

Another gripe I have, and I do not mind citing it, is the one I have taken up with WedMD. These guys are not reliable when they say beta glucan should not be taken for more than a week consecutively. I have asked them, “Where is your resource on this subject?” I have customers who have taken very high doses of beta glucan daily for more than a decade and they are healthy as can be. Their children, and now their children’s children, are taking high doses of Beta Glucan on a daily basis. I have never had ONE person who has ever had a side effect where some doctor said “Beta Glucan is the reason for this side effect.” It is probably one of the safest, if not THE SAFEST compound you can put in your body. This includes Vitamin C and Vitamin A, as you can ingest toxic levels of these vitamins. So those are my three biggest issues that I see floating around out there. After 15 years, I feel we have done a good job educating our customers and encouraging them to do their due diligence. Therefore, I believe the tide is slowly turning against these urban legends and false rumors.

As Answered By
Dr. Vaclav Vetvicka

Not really, but I mentioned there are fights between the mushroom glucan groups and yeast glucan groups and about which is better. There was also a fight about which size is better. There was a time when we first tried to inject the glucan, which later we found it is not the ideal way to do it. And also we didn’t know how the whole process worked. As I mentioned, how it goes through the cells and how the cells will distribute it slowly. We couldn’t imagine how the big, really large glucans would be able to do something with the cells. So there was kind of an idea that smaller might be better. But now we know exactly how the cells are chewing it up into smaller pieces and releasing it and it is caught again and it goes back and forth. So there is absolutely no reason to believe a smaller glucan would do any better action.

Most probably it’s not. You have to remember that a lot of companies are to some extent hiding behind claims of patented manufacturing processes. They are not actually lying, they have the patents on how to make it. It is rather easy to get a patent on manufacturing glucan. Because at one step if you change the temperature, you immediately have a new process and you get a patent for it. It still doesn’t say the glucan is better and very few companies have patents on glucans showing that this particular glucan that they make is better in activity than the other glucans. So you can say whatever you want, the internet will accept a lot of things, a lot of statements. But if you cannot back it up with good science, it’s just your private statement.

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Dr. Vaclav Vetvicka

Dr. Vaclav Vetvicka is a Professor and Vice Chairman, Director of Research at the Department of Pathology and Laboratory Medicine, University of Louisville. Dr. Vetvicka graduated in 1978 from Charles University in Prague with a doctorate degree in biology and obtained his Ph.D. in 1983 from the Czechoslovak Academy of Sciences, Institute of Microbiology.